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A Giant Heterometallic Polyoxometalate Nanocluster for Enhanced Brain-Targeted Glioma Therapy
N. Song, M. Lu, J. Liu, M. Lin, P. Shangguan, J. Wang,* B. Shi,* and J. Zhao*. Angewandte Chemie International Edition. 2024, e202319700 (IF=16.60, Back cover, VIP文章)
A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease
J. Wang,# P. Shangguan,# X. Chen, Y. Zhong, M. Lin, M. He, Y. Liu, Y. Zhou, X. Pang, L. Han, M. Lu, X. Wang, Y. Liu, H. Yang, J. Chen, Ch. Song, J. Zhang,* X. Wang,* B. Shi* & B. Z. Tang*. Nature Communications 2024, 15, 705.(IF=16.6)
Dual-Site Förster Resonance Energy Transfer Route of Upconversion Nanoparticles-Based Brain-Targeted Nanotheranostic Boosts the Near-Infrared Phototherapy of Glioma
J. Wang,# P. Shangguan,# M. Lin, L. Fu, Y. Liu, L. Han, S. Chen, X. Wang, M. Lu, Z. Luo, Y. Zhong,* B. Shi,* F. Bai*. ACS Nano 2023, 17, 16840−16853 (IF=17.0997)​
Cancer cell-mitochondria hybrid membrane coated Gboxin loaded nanomedicines for glioblastoma treatment
Y. Zou, Y. Sun, Y. Wang, D. Zhang, H. Yang, X. Wang , M. Zheng & B. Shi*. Nature Communications 2023, 14, 4557 (IF=16.6)
Liquid–liquid phase separation of amyloid-β oligomers modulates amyloid fibrils formation
X. Gui, S. Feng, Z. Li, Y. Li, B. Reif*, B. Shi*, and Z. Niu*. Journal of Biological Chemistry. 2023, 299(3), 102926. (IF=5.485)​
IGFBP5 is an ROR1 ligand promoting glioblastoma invasion via ROR1/HER2-CREB signaling axis
W. Lin,# R. Niu,# S.-M. Park,# Y. Zou,# S. S. Kim,# X. Xia, S. Xing, Q. Yang, X. Sun, Z. Yuan, S. Zhou, D. Zhang, H. Joon Kwon, S. Park, C. I. Kim, H. Koo, Y. Liu, H. Wu, M. Zheng, H. Yoo, B. Shi,* J. B. Park*, J. Yin*. Nature Communications 2023,14,1578.
A Brain-Targeting NIR-II Ferroptosis System: Effective Visualization and Oncotherapy for Orthotopic Glioblastoma
J. Zhang, L. Han, H. Wu, Y. Zhong, P. Shangguan, Y. Liu, M. He, H. Sun, C. Song, X. Wang, Y. Liu, J. Wang,* L. Zheng,* B. Shi,* and B. Z. Tang*. Advanced Science. 2023, 2206333. (IF=17.521)
Non-invasive PTEN mRNA brain delivery effectively mitigates growth of orthotopic glioblastoma
Y. Liu,# D. Zhang,# Y. An, Y. Sun, J. Li, M. Zheng,* Y. Zou,* B. Shi.*. Nano Today 2023, 49,101790. (IF=18.962)
Exosomes based strategies for brain drug delivery
F. U. Rehman, Y. Liu, M. Zheng* , B. Shi*. ​Biomaterials 2023, 293, 121949 (IF=15.305)​
Near-Infrared Aggregation-Induced Emission Luminogens for In Vivo Theranostics of Alzheimer’s Disease
T. Zhang,# X. Chen,# C. Yuan, X. Pang, Shangguan P., Y. Liu, L. Han, J. Sun, J. W. Y. Lam, Y. Liu, J. Wang,* B. Shi,* B. Z. Tang.* Angew. Chem. Int. Ed. 2022, e202211550. (IF=16.823)
Near infrared-activatable biomimetic nanogels enabling deep tumor drug penetration inhibit orthotopic glioblastoma
D. Zhang,# S. Tian,# Y. Liu, M. Zheng, X. Yang, Y. Zou,* B. Shi,* L. Luo.* Nature Communications 2022, 13, 6835. (IF=17.694)
A Biomimetic Nanomedicine Targets Orthotopic Glioblastoma by Combinatorial Co-Delivery of Temozolomide and a Methylguanine-DNA Methyltransferase Inhibitor
Y. Wang, Y. Sun, N. Geng, M. Zheng, Y. Zou,* and B. Shi.* Advanced Therapeutics 2022, 2200095. (IF=5.003)
Biomimetic Dp44mT-nanoparticles selectively induce apoptosis in Cu-loaded glioblastoma resulting in potent growth inhibition
M. Ismail,# W. Yang,# Y. Li,# Y. Wang, W. He, J. Wang, P. Muhammad, T. B. Chaston, F. U. Rehman, M. Zheng, D. B. Lovejoy,* B. Shi.* Biomaterials 2022, 289, 121760 (IF=15.305)​
Brain-Targeting Metastatic Tumor Cell Membrane Cloaked Biomimetic Nanomedicines Mediate Potent Chemodynamic and RNAi Combinational Therapy of Glioblastoma
D. Zhang, Y. Sun, S. Wang, Y. Zou,* M. Zheng,* and B. Shi.* Advanced Functional Materials 2022, 2209239 (IF=19.925)
Brain-targeted CRISPR/Cas9 nanomedicine for effective glioblastoma therapy
W. Ruan,# M.Jiao,# S. Xu,# M. Ismail, X. Xie, Y. An, H. Guo, R. Qian,* B. Shi,* M. Zheng.* Journal of Controlled Release 2022, 351, 739–751 (IF=11.467)
Arsenic Prodrug-Mediated Tumor Microenvironment Modulation Platform for Synergetic Glioblastoma Therapy
J. Yan,# S. Hanif,# D. Zhang, M. Ismail, X. Wang, Q. Li, B. Shi, P. Muhammad,* H. Wu.* ACS Applied Materials & Interfaces 2022, 14, 32, 36487–36502 (IF=10.383)
Brain Codelivery of Temozolomide and Cisplatin for Combinatorial Glioblastoma Chemotherapy
Y. Zou,# Y. Wang,# S. Xu, Y. Liu, J. Yin, D. B. Lovejoy, M. Zheng, X-J Liang, J. B. Park, Y. M. Efremov, I. Ulasovand, B. Shi.* Advanced Materials 2022, 34, 2203958 (IF=32.085)
Carbon dots supported single Fe atom nanozyme for drug-resistant glioblastoma therapy by activating autophagy-lysosome pathway
P. Muhammad,# S. Hanif,# J. Li, A. Guller, F. U. Rehman, M. Ismail, D. Zhang, X. Yan,* K. Fan,* B. Shi.* Nano Today 2022, 45, 101530 (IF=18.962)
Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma
M. Ismail,# W. Yang,# Y. Li, T. Chai, D. Zhang, Q. Du, P. Muhammad, S. Hanif, M. Zheng,* B. Shi.* Biomaterials 2022, 287, 121608. (IF=15.305)
Blood-brain barrier–penetrating single CRISPR-Cas9 nanocapsules for effective and safe glioblastoma gene therapy
Y. Zou,# X. Sun,# Q. Yang, M. Zheng,* O. Shimoni, W. Ruan, Y. Wang, D. Zhang, J. Yin, X. Huang, W. Tao, J. B. Park, X-J Liang, K. W. Leong, B. Shi.* ​Science Advances 2022, 8, eabm8011.(IF=14.98)
Brain co-delivery of first-line chemotherapy drug and epigenetic bromodomain inhibitor formultidimensional enhanced synergistic glioblastoma therapy
Y. Liu, W. Wang, D. Zhang, Y. Sun, F. Li, M. Zheng, D. B. Lovejoy, Y. Zou,* B. Shi.* Exploration 2022, 20210274.
Brain-targeted polymersome codelivery of siRNA and temozolomide for effective glioblastoma chemo-RNAi synergistic therapy
M. Zheng,# C. Yan,# Q. Yang, F. Zhu, Q. Du, X. Xia, M. Morsch, A. Lee, J. Yin, Y. Zou, B. Shi.* ChemPhysMater 2022, 1, 203–210.
Heme Oxygenase-1 targeting exosomes for temozolomide resistant glioblastoma synergistic therapy
F. U. Rehman,# Y. Liu,# Q. Yang#, H. Yang, R. Liu, D. Zhang, P. Muhammad, Y. Liu, S. Hanif, M. Ismail, M. Zheng,* B. Shi.* Journal of Controlled Release 2022, 345,696–708.(IF=11.467)
Brain-Targeted Codelivery of Bcl-2/Bcl-xl and Mcl‑1 Inhibitors by Biomimetic Nanoparticles for Orthotopic Glioblastoma Therapy
W. He, X. Li, M. Morsch, M. Ismail, Y. Liu, F. U. Rehman, D. Zhang, Y. Wang, M. Zheng, R. Chung, Y. Zou,* and B. Shi.* ACS Nano 2022, 16, 6293−6308. (IF=18.028)
Nanotechnology-Based Strategies for Early Diagnosis of Central Nervous System Disorders
S. Hanif, P. Muhammad, Z. Niu, M. Ismail, M. Morsch, X. Zhang,* M. Li,* and B. Shi*. Advanced Nanobiomed Research​ 2021, 1, 2100008.
Influence of Water and Enzyme on the Post-Transition State Bifurcation of NgnD-Catalyzed Ambimodal [6+4]/[4+2] Cycloaddition
X. Wang,# C. Zhang,# Y. Jiang, W. Wang, Y. Zhou, Y. Chen, B. Zhang, R. X. Tan, H. M. Ge,* Z. J. Yang,* and Y. Liang* Journal of the American Chemical Society. 2021, 143, 21003−21009. (IF=16.383)
多功能Aβ 有机小分子探针的构建及 诊疗应用进展
陈晓宇,刘义升,何牧,上官萍,韩璐璐,王杰菲*,师冰洋*. 高等学校化学学报 2021, 11, 3310-3320.
Brain-Targeted Aggregation-Induced-Emission Nanoparticles with Near-Infrared Imaging at 1550 nm Boosts Orthotopic Glioblastoma Theranostics
J. Wang, Y. Liu, M. Morsch, Y. Lu, P. Shangguan, L. Han, Z. Wang, X. Chen, C. Song, S. Liu,* B. Shi,* and B. Z. Tang*. Advanced Materials 2021, 2106082 (IF=32.085)
Polymeric Nanoparticles for Mitochondria Targeting Mediated Robust Cancer Therapy
Y. Sun, Q. Yang, X. Xia, X. Li, W. Ruan, M. Zheng, Y. Zou*, B. Shi.* Frontiers in Bioengineering and Biotechnology 2021, 9, 755727.(IF=6.064)
From mouse to mouse-ear cress: Nanomaterials as vehicles in plant biotechnology
X. Xia, B. Shi,* L. Wang et al. Exploration 2021, 1, 9–20.
Editorial: Application for Nanotechnology for the Treatment of Brain Diseases and Disorders
J. Li, M. Zheng, Y. Zou, P. C. Ke, M. Zhang, W. A. Banks and B. Shi* ​Frontiers in Bioengineering and Biotechnology. 2021, 9, 743160. (IF=6.064)
Development of Novel Therapeutics Targeting the Blood–Brain Barrier: From Barrier to Carrier
J. Li, M. Zheng, O. Shimoni, W. A. Banks, A. I. Bush, J. R. Gamble, and B. Shi*. Advanced Science. 2021, 8, 2101090 (IF=17.521)
Cation-Free siRNA Micelles as Effective Drug Delivery Platform and Potent RNAi Nanomedicines for Glioblastoma Therapy
T. Jiang, Y. Qiao, W. Ruan, D. Zhang, Q. Yang, G. Wang, Q. Chen, F. Zhu, J. Yin, Y. Zou, R. Qian, M. Zheng,* and B. Shi*. Advanced Materials. 2021, 2104779. (IF=32.085)
Tuning the Elasticity of Polymersomes for Brain Tumor Targeting
M. Zheng#, Q. Du#, X. Wang, Y. Zhou, J. Li, X. Xia, Y. Lu, J. Yin, Y. Zou, J. B. Park, and B. Shi*. Advanced Science. 2021, 2102001 (IF=17.521)
Polymeric nanoparticle mediated inhibition of miR-21 with enhanced miR-124 expression for combinatorial glioblastoma therapy
Y. Liu, M. Zheng*, M. Jiao, C. Yan, S. Xu, Q. Du, M. Morsch, J. Yin, B. Shi*. Biomaterials 2021, 276, 121036. (IF=15.305)
Light: A Magical Tool for Controlled Drug Delivery.
Y. Tao, H. F. Chan, B. Shi,* M. Li,* and K. W. Leong*. Advanced functional materials. 2020, 2005029. (IF=19.925)
​Blood-brain barrier–penetrating siRNA nanomedicine for Alzheimer's disease therapy.
Y. Zhou#, F. Zhu#, Y. Liu#, M. Zheng*, Y. Wang, D. Zhang, Y. Anraku, Y. Zou, J. Li, H. Wu, X. Pang, W. Tao, O. Shimoni, A. I. Bush, X. Xue*, B. Shi*. Science Advances 2020, 6, eabc7031. (IF=14.98)
A Robust Intrinsically Green Fluorescent Poly(Amidoamine) Dendrimer for Imaging and Traceable Central Nervous System Delivery in Zebrafish
G. Wang, X. Zhao, H. Wu, D. B. Lovejoy, M. Zheng, A. Lee, L. Fu, K. Miao, Y. An, N. Sayyadi, K. Ding, R. S. Chung, Y. Lu, J. Li,* M. Morsch,* and B. Shi*. Small. 2020, 2003654. (IF=15.154)
ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages.
J. Yin*, S. Kim, E. Choi, Y. T. Oh, W. Lin, T-H Kim, J. K. Sa, J. H. Hong, S. H. Park, J. Lee, D-H Nam, K. S. Choi, B. Shi, H-S Gwak, H. Yoo, A. Iavarone*, J. H. Kim*, J. B. Park*. Nature Communications. 2020, 11: 2978 (IF=17.694)
Advances in Nanotechnology-based strategies for the treatments of amyotrophic lateral sclerosis.
G. Wang, S. Rayner, R. Chung, B. Shi*, X.-J. Liang*. ​Materials Today Bio 2020, 6, 100055.(IF=10.762)
Stimuli-Responsive Prodrug-based Cancer Nanomedicine.
A. Xie#, S. Hanif#, O. Jiang*, Z. Tang, N. Kong, N. Y. Kim, B. Qia, B. Shi*, W. Tao*. EBioMedicine 2020, 56, 102821. (Invited Review) (IF=11.205)
Nanomedicine-based Immunotherapy for Central Nervous System Disorders.
S. Hanif#, P. Muhammad#, R. Chesworth, F. U. Rehman, R. Qian*, M. Zheng*, B. Shi*. Acta Pharmacologica Sinica 2020, 41, 936-953. (Invited Review) (IF=7.165)
Single siRNA Nanocapsules for Effective siRNA Brain Delivery and Glioblastoma Treatment.
Y. Zou, X. Sun, Y. Wang, C. Yan, Y. Liu, J. Li, D. Zhang, M. Zheng*, R. S. Chung and B. Shi*. Advanced Materials. 2020, 2000416 (IF=32.085)
Evaluation of nanomechanical properties of hyperbranched polyglycerols as prospective cell membrane engineering block.
H. Wu#*, Q. Chen#, M. Jiao, X. Xia, X. Lian, N. Huang, K. Li, J. Yin, B. Shi*. Colloids and Surfaces B: Biointerfaces 2020, 190, 110968. (IF=5.999)
Evolution of hyperbranched polyglycerols as single-dopant carriers.
H. Wu#*, Q. Chen#, N. Huang, X. Lian, K. Li. Colloids and Surfaces A-Physicochemical and Engineering Aspects 2020, 592, 124608. (IF=5.518)
Charge Conversional Biomimetic Nanocomplexes as a Multifunctional Platform for Boosting Orthotopic Glioblastoma RNAi Therapy.
Y. Liu,# Y. Zou,# C. Feng,# A. Lee, J. Yin, R. Chung, J. B. Park, H. Rizos, W. Tao, M. Zheng,* O. C. Farokhzad,* B. Shi*. Nano Letters. 2020, 20, 1637–1646. (IF=11.189)
SERS-based Nanostrategy for Rapid Anemia Diagnosis.
P. Muhammad#, S. Hanif#, J. Yan, F. U. Rehman, J. Wang, M. Khan, R. Chung, A. Lee, M. Zheng*, Y. Wang*, B. Shi*. Nanoscale. 2020, 12, 1948–1957. (IF=8.307)
聚合物纳米药物用于治疗脑胶质瘤的最新研究进展
孙雅静, 王一斌, 刘艳杰, 邹艳,* 郑蒙, 师冰洋*. 中国科学:生命科学, 2021, 51, 819-835
生物细胞仿生药物递送系统在癌症治疗中的应用
何文亚, 邹艳*, 郑蒙, 师冰洋*. 中国科学:化学, 2019. 49: 1203–1212.
Central metal-derived co-assembly of biomimetic GdTPP/ZnTPP porphyrin nanocomposites for enhanced dual-modal imaging-guided photodynamic therapy.
J. Wang,# Z. Wang,# Y. Zhong, Y. Zou, C. Wang, H. Wu, A. Lee, W. Yang , X. Wang, Y. Liu, D. Zhang, J. Yan, M. Hao, M. Zheng, R. Chung, F. Bai,* B. Shi*. Biomaterials 2020, 229, 119576. (IF=15.305)
ROS Responsive Polymeric siRNA Nanomedicine Stabilized by Triple-Interactions for the Robust Glioblastoma Combinational RNAi Therapy.
M. Zheng,# Y. Liu,# Y. Wang, D. Zhang, Y. Zou, W. Ruan, J. Yin, W. Tao, J. B. Park, and B. Shi*. Advanced Materials. 2019, 1903277.(IF=32.085)
The siRNAsome: A Cation Free and Versatile Nanostructure for siRNA and Drug Codelivery. ​
M. Zheng,# T. Jiang,# W. Yang, Y. Zou, H. Wu, X. Liu, K. McDonald, D. Ling, J. Shi, F. Zhu, R. Qian and B. Shi*. Angewandte Chemie International Edition. 2019, 58, 4938–4942. (IF=16.823)
Bioreducible Zinc(II)−Dipicolylamine Functionalized Hyaluronic Acid Mediates Safe siRNA Delivery and Effective Glioblastoma RNAi Therapy.
M. Zheng#, Z. Yang#, S. Chen#, H. Wu, Y. Liu, A. Wright, J. Lu, X. Xia, A. Lee, J. Zhang, H. Yin*, Y. Wang*, W. Ruan*, X. Liang. ACS Applied Bio Materials. 2019; 2: 362–369.
Developing a pH-sensitive Al(OH)3 layer mediated UCNP@Al(OH)3/Au nanohybrids for photothermal therapy and fluorescence imaging in vivo.
J. Chen#, D. Zhang#, Y. Zou, Z. Wang, M. Hao, M. Zheng, X. Xue, X. Pan, Y. Lu, J. Wang*, B. Shi*. Journal of Materials Chemistry B. 2018; 6: 7862-7870. (IF=7.571)
Stilbenes from Veratrum maackii Regel Protect against Ethanol-Induced DNA Damage in Mouse Cerebellum and Cerebral Cortex. ​
Y. Wu, S. Li, J. Liu, X. Liu, W. Ruan, J. Lu, Y. Liu, T. Lawson, O. Shimoni, D. B. Lovejoy, A. K. Walker, Y. Cong*, B. Shi*. ACS Chemical Neuroscience. 2018; 9(7): 1616-1624. (IF=5.78)
​Effective and Targeted Human Orthotopic Glioblastoma Xenografts Therapy via a Multifunctional Biomimetic Nanomedicine.
Y. Zou#, Y. Liu#, Z. Yang, D. Zhang, Y. Lu, M. Zheng*, X. Xue, J. Geng, R. Chung, B. Shi*. Advanced Materials. 2018; 30: 1803717. (IF=32.085)
Large-area gold nanohole arrays fabricated by one-step method for surface plasmon resonance biochemical sensing.
H. Qi, L. Niu, J. Zhang, J. Chen, S. Wang, J. Yang, S. Guo, T. Lawson, B. Shi*, C. Song*. Science China-Life Sciences. 2018; 61: 476-482. (invited paper, IF=10.385)
DNA nanoclew templated spherical nucleic acid for siRNA delivery.
W. Ruan, M. Zheng*, Y. An, Y. Liu, D. Lovejoy, M. Hao, Y. Zou, A. Lee, S. Yang, Y. Lu, M. Morsch, R. Chung, B. Shi*. Chemical Communications. 2018; 54: 3609-3612.(IF=6.065)
Nanotechnology based strategies for siRNA brain delivery for disease therapy.
​M. Zheng, W. Tao, Y. Zou, O. C. Farokhzad, B. Shi*. Trends in Biotechnology. 2018; 36: 562-575. (IF=21.942)
A versatile upconversion surface evaluation platform for bio–nano surface selection for the nervous system.
L. Fu, M. Morsch, B. Shi*, G. Wang, A. Lee, R. Radford, Y. Lu, D. Jin, R. Chung. Nanoscale. 2017; 9: 13683. (IF=8.307)
Multifunctional hybrid nanoparticles for traceable drug delivery and intracellular microenvironment-controlled multistage drug-release in neurons.
B. Shi*, X. Du*, J. Chen, L. Fu, M. Morsch, A. Lee, Y. Liu, N. Cole, R. Chung. Small. 2017; 3: 1603966. (IF=15.305)
Stable upconversion nanohybrid particles for specific prostate cancer cell immunodetection.
Y. Shi, B. Shi*, A. V. E. Dass, Y. Lu, N. Sayyadi, L. Kautto, R. D. Willows, R. Chung, J. Piper, H. Nevalainen, B. Walsh, D. Jin, N. H. Packer. Scientific Reports. 2016; 6: 37533.(IF=4.997)
Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn3[Co(CN)6]2 nanocubes.
J. Chen, M. He, P. Xu, H. Wu, Z. Guo*, B. Shi*, Q. Chen*. RSC Advances. 2016; 6: 84810. (IF=4.036)
Challenges in DNA delivery and recent advances in multifunctional polymeric DNA delivery dystems.
B. Shi*, M. Zheng, W. Tao, R. Chung, D. Jin, D. Ghaffari, O. C. Farokhzad*. Biomacromolecules. 2017; 18: 2231-2246. (IF=6.979)
One-step conjugation of glycyrrhetinic acid to cationic polymers for high-performance gene delivery to cultured liver cell.
Y. Cong, B. Shi*, Y. Lu, S. Wen, R. Chung, D. Jin. Scientific Reports. 2016; 6: 21891. (IF=4.997)
 
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