吴海刚,讲师,硕士生导师
E-mail: whg_2018@henu.edu.cn
研究领域:人工调控血脑屏障通透性及分子机制、体外血脑屏障模型的构建及理论模型构建。
2011年毕业于郑州大学化学系,2014年毕业于华东师范大学生命科学学院(导师:刘明耀教授/陈益华教授),2018年毕业于上海交通大学生物医学工程学院获工学博士学位(导师:但亚平教授)。2018年1月入职河南大学-麦考瑞大学生物医学联合创新中心,并入选中原英才计划青年拔尖人才。现承担省厅级项目2项,在ACS Applied Materials & Interfaces, Journal of Clinical Investigation, NPG Asia Materials, Small, Polymer Chemistry, Colloid and surface B: Biointerfaces等杂志发表SCI论20余篇,其中以第一作者/通讯作者身份发表论文10篇。
承担项目:
1. 光动力控制血脑屏障及改善替莫唑胺脑胶质瘤治疗的研究,2020/01/01-2022/12/31,河南省科技攻关项目,10万元,主持,在研;
2. 基于上转换纳米晶的肿瘤循环细胞检测及分离,2019/01-2020/12,河南省中原博士后创新计划支持,50万元,结题。
代表性论文
1. Wang G#, Zhao X#, Wu H#, Lovejoy DB, Zheng M, Lee A, Fu L, Miao K, An Y, Sayyadi N, Ding K, Chung RS, Lu Y, Li J, Morsch M, Shi B. "A robust intrinsically green fluorescent poly (Amidoamine) dendrimer for imaging and traceable central nervous system delivery in zebrafish." Small 16.39 (2020): 2003654.
2. Haigang Wu, Ting Yin, Ke Li, Ruibin Wang, Yantian Chen and Lili Jing. "Encapsulation property of hyperbranched polyglycerols as prospective drug delivery systems." Polymer Chemistry 9.3 (2018): 300-306.
3. Hu K, Li K, Lv J, Feng J, Chen J, Wu H, Cheng F, Jiang W, Wang J, Pei H, Chiao PJ, Cai Z, Chen Y, Liu M, Pang X.. "Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma." The Journal of clinical investigation 130.4 (2020).
4. Wu H, Chen Q, Jiao M, Xia X, Lian X, Huang N, Li K, Yin J, Shi B. "Evaluation of nanomechanical properties of hyperbranched polyglycerols as prospective cell membrane engineering block." Colloids and Surfaces B: Biointerfaces 190 (2020): 110968.
5. Wu H, Li K, Gao X, Dan Y. "Phosphorus ionization in silicon doped by self-assembled macromolecular monolayers." AIP Advances 7.10 (2017): 105310.
课题组成员:
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杨稳源(2022硕士) | 王欣(2023硕士) | 沈冰燕(2023硕士) | 马瑞(2024硕士) | 韩依晴(2024硕士) |
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李琪(2024硕士) |
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