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Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn3[Co(CN)6]2 nanocubes. 

Jian Chen, Mengni He, Pengping Xu, Huihui Wu, Zhen Guo,* Bingyang Shi* and Qianwang Chen*

RSC Advances. 2016; 6: 84810. (IF=4.036)

Abstract

Luminescent Mn3[Co(CN)6]2 nanocubes doped with Cd2+ can induce  human lung adenocarcinoma cells A549 generating more metallothioneins  (MTs) than squamous cells H520. The nanocubes can be  bound to MTs and be excluded from cells for detoxification. Then  A549 cells have a lower fluorescence imaging intensity than H520  cells, which can distinguish the two kinds of cells.




 
? 2017 河南大学-麦考瑞大学
生物医学联合创新中心
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  地址
河南省开封市
河南大学金明校区,生命科学学院
475004
 技术支持:河南科加
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邮箱: jcbi@vip.henu.edu.cn
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